Formulation test of facial serum mangosteen rind extract (Garcinia Mangostana) and niacinamide

Authors

  • Mia Marlina Department of pharmacy, Sekolah Tinggi Ilmu Kesehatan Mitra Keluarga
  • Maya Uzia Beandrade Department of pharmacy, Sekolah Tinggi Ilmu Kesehatan Mitra Keluarga
  • Intan Kurnia Putri Department of pharmacy, Sekolah Tinggi Ilmu Kesehatan Mitra Keluarga
  • Reza Anindita Department of pharmacy, Sekolah Tinggi Ilmu Kesehatan Mitra Keluarga

Keywords:

Mangosteen Rind Extract; Niacinamide ; Facial Serum ; Physical Stability Test

Abstract

Facial serum can be described as a product that contains active ingredients to treat skin and fade acne scars. Mangosteen peel has benefits as an antibacterial. The ingredients contained in the mangosteen rind are flavonoids, alkaloids, and phenols. The research design used was pre-experimental, using mangosteen rind samples. The physical stability test was carried out by organoleptic, homogeneity, pH, and viscosity tests for 14 days. Data analysis was performed with a descriptive test. The results of the phytochemical screening test on the flavonoid, phenol, and alkaloid tests obtained positive results. Organoleptic test results during 14 days of storage did not change color and smell. pH test results on F1 6.33- 6.41; F2 5.85-6.06 ; and on F3 5.48-5.69. Homogeneity test results on the three homogeneous formulas, and the F1 viscosity test 10,333- 22,500 cP; F2 11.000-21.667 cP; and F3 10.833-21.333 cP. It can be found that the decrease in the pH value was found in F1 (1%) by 0.15%, F2 (3%) by 3.4% and F3 (5%) by 3%. The decrease in viscosity in F1 (1%) was 54%, F2 (3%) was 49.22%, and F3 (5%) was 49.21%. So, it is necessary to add observation time in order to obtain information on the physical stability of a good serum preparation formula.

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Published

2023-12-19