Synergism test on date seeds (Phoenix dactylifera l.) And peanut shells (Arachis hypogea l.) Extract on antioxidant activity

Authors

  • Galuh Anjani Garnisaputri Department of pharmacy, Sekolah Tinggi Ilmu Kesehatan Mitra Keluarga
  • Intan Kurnia Putri Department of pharmacy, Sekolah Tinggi Ilmu Kesehatan Mitra Keluarga
  • Melania Perwitasari Department of pharmacy, Sekolah Tinggi Ilmu Kesehatan Mitra Keluarga
  • Dede Dwi Nathalia Department of pharmacy, Sekolah Tinggi Ilmu Kesehatan Mitra Keluarga

Keywords:

Antioxidant activity; Cancer; Date seeds; FRAP; Peanut skin; Synergism

Abstract

Free radicals can cause body tissue damage and cancer. Several compounds that can overcome tissue damage in the body are called antioxidant compounds. Antioxidant compounds can be found in various plants, such as dates and peanuts. The purpose of this study was to evaluate the antioxidant activity contained in date seeds and peanut skin as well as the synergistic effect of the combination of date seed extract and peanut shell extract. The samples used were ethanolic extract of date palm seeds and peanut shells by maceration extraction method. The Ferric Reducing Antioxidant Power (FRAP) method with UV-Vis spectrophotometry was applied to evaluate the antioxidant activity. The results of the phytochemical screening showed that the ethanol extract of date palm seeds and the ethanol extract of peanut shells contained flavonoid compounds characterized by a change in color to orange and phenolic compounds indicated by a change in color to black. The results of antioxidant activity using the FRAP method were 130.370% for date seed extract and 170.353% for peanut shell extract. Combining the ethanolic extract of date palm seeds and the ethanol extract of peanut shells obtained a percentage difference value of 78.575%. Peanut shell extract has higher antioxidant activity than date seed extract, and combining the two has a synergistic effect.

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Published

2023-12-19