Phytochemical screening of japanese papaya leaf extracts (cnidoscolus aconitifolius mill.) With the maceration method using different types of solvents

Abstract

Introduction: Japanese Papaya Leaf is a wild bush plant that grows up to 6 meters, and this leaf is easy to grow in
tropical countries like Indonesia. The flavonoid compounds contained can lower cholesterol levels in the blood.
Method: In this study, population and samples of Japanese Papaya Leaf (Cnidoscolus aconitifolius Mill.) were used
that grow in Bekasi Timur Regency, Bekasi. This research is an experimental qualitative descriptive study that aims
to determine the results of the macroscopic examination, and phytochemical screening using a test tube on Japanese
papaya leaves extracted by maceration using 70% ethanol, n-hexane, and aqua distillate as solvents. Results: The results
of the research uses an macroscopic examination, which included leaf morphology test showed dark green color with a
slightly shiny slippery surface and round and finger shape leaves. The results of the extract yield from various solvents,
obtained aqua distillate by 27%, ethanol 70% by 10.2%, and n-hexane by 4.5%. In this case the amount of yield has a
different polarity. Phytochemical screening test of Japanese Papaya leaf extract from 70% ethanol and aqua distillate
show positive for alkaloids, flavonoids, saponins, triterpenoids/steroids, tannins, while for n-hexane solvent showed
positive for flavonoids and steroids. Conclusion: The conclusion of this study is that extracts from Japanese Papaya
leaves contain secondary metabolites, namely alkaloids, flavonoids, saponins, tannins,triterpenoids and steroids.